Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 12;23(8):4262. doi: 10.3390/ijms23084262

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The C-6 effectively alleviates PFF-induced ROS generation and protein aggregation. (A) The example images support that PFF-induced ROS generation and protein aggregates were substantially reversed by the C-6 treatment, compared with no PFF. (B,C) The C-6 treatment significantly ameliorated both protein aggregation and ROS generation, induced by PFF exposure. The optimal concentration used was 1 µM, at which ROS generation and protein aggregation were significantly reduced with the C-6. One-way ANOVA with Dunnett’s test was applied to compare the effect of the treatment with PFF only (#) (n = 3 or 4 independently). ****: p < 0.0001.