Table 2.

Mean, standard deviation of incidence of diseases before and during COVID-19, and their difference in the subgroup by sex.

Diseases	Before COVID-19		During COVID-19		p-Values of Difference
	Mean	SD	Mean	SD	Mean	Variance
Men
Depressive disorder	93,001.0	4416.1	103,448.4	3957.7	<0.001 *	<0.001 †
Bipolar disorder	18,939.4	999.0	20,628.0	537.7	<0.001 *	<0.001 †
Primary insomnia	62,275.8	4002.0	70,463.9	2474.7	<0.001 *	<0.001 †
Schizophrenia	36,100.1	741.9	35,035.8	446.3	<0.001 *	<0.001 †
Panic disorder	32,491.6	2103.5	37,652.8	1529.4	<0.001 *	<0.001 †
Hypochondriasis	367.3	18.9	487.4	88.1	<0.001 *	<0.001 †
Posttraumatic stress disorder	1016.6	84.1	1209.3	97.0	<0.001 *	<0.001 †
Anxiety disorder	88,061.0	4359.1	98,208.9	3824.1	<0.001 *	<0.001 †
Anorexia nervosa	125.0	21.6	147.8	18.1	0.004 *	0.001 †
Addephagia	56.7	7.1	54.6	5.9	0.283	0.352
Alcoholism	15,908.8	388.4	14,929.1	422.6	<0.001 *	<0.001 †
Nicotine dependency	338.4	42.9	267.1	30.0	<0.001 *	<0.001 †
Gambling addiction	284.1	30.6	397.7	68.6	<0.001 *	<0.001 †
Women
Depressive disorder	199,619.1	9033.8	228,208.2	11,259.4	<0.001 *	<0.001 †
Bipolar disorder	28,128.2	1735.0	32,342.3	1176.9	<0.001 *	<0.001 †
Primary insomnia	95,414.7	5747.8	107,826.9	4878.0	<0.001 *	<0.001 †
Schizophrenia	43,129.3	895.2	42,683.3	647.1	0.036 *	0.099
Panic disorder	36,140.3	2746.4	43,687.8	2437.3	<0.001 *	<0.001 †
Hypochondriasis	337.5	24.0	408.4	35.6	<0.001 *	<0.001 †
Posttraumatic stress disorder	1589.9	148.0	2002.1	184.8	<0.001 *	<0.001 †
Anxiety disorder	126,997.6	6125.2	145,837.7	7225.4	<0.001 *	<0.001 †
Anorexia nervosa	479.9	75.5	581.3	41.3	<0.001 *	<0.001 †
Addephagia	633.9	41.3	777.5	64.9	<0.001 *	<0.001 †
Alcoholism	3339.4	115.7	3559.9	147.5	<0.001 *	<0.001 †
Nicotine dependency	42.0	10.4	41.5	7.4	0.947	0.863
Gambling addiction	13.5	3.8	16.4	3.2	0.018 *	0.016 †

* Mann–Whitney U test, significance at <0.05. ^† Levene’s test in non-parametric data, significance at <0.05.