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. 2022 Mar 23;11(4):384. doi: 10.3390/pathogens11040384

Figure 2.

Figure 2

The effect of TBEV infection (TBE1) and TBEV+Bb/Ap co-infection (TBE+LD1) as well as therapy (TBE2 and TBE+LD2) on the effectiveness of the Nrf2 (A) transcription factor, visible in the expression of Nrf2/pNrf2 (B), HO-1 (C) and KEAP1 (D) assessed in granulocytes of patients and compared to healthy subjects (control). The mean values for TBE patients (before–TBE1 and after treatment–TBE2, n = 40), patients with TBE+LD (before–TBE+LD1 and after treatment–TBE+LD2, n = 6) and control subjects (n = 20) with SD are shown as follows: x—differences vs. control group, p < 0.05; a—differences vs. TBE1 group, p < 0.05; b—differences vs. TBE+LD1 group, p < 0.05.