Table 1.
Participants’ characteristics at baseline.
| Parameters | Aspartame | 10% HFCS | 17.5% HFCS | 25% HFCS |
|---|---|---|---|---|
| Age (years) | 25.4 ± 6.2 1 | 27.7 ± 6.0 | 24.1 ± 5.0 | 26.8 ± 6.6 |
| Sex (M/F) | 11/12 | 9/9 | 7/9 | 15/13 |
| Weight (kg) | 71.8 ± 10.6 | 70.9 ± 10.3 | 69.9 ± 14.3 | 72.9 ± 14.5 |
| BMI (kg/m2) | 24.8 ± 3.3 | 24.9 ± 3.8 | 24.2 ± 3.3 | 24.9 ± 4.0 |
| Waist circumference (cm) | 75.2 ± 6.4 | 76.2 ± 9.3 | 73.3 ± 7.7 | 77.0 ± 10.1 |
| Body fat (%) | 27.1 ± 9.8 | 26.8 ± 9.8 | 25.9 ± 9.9 | 26.0 ± 9.7 |
|
Energy requirement
(kcal/d) |
2354 ± 322 | 2323 ± 247 | 2326 ± 375 | 2390 ± 350 |
|
Systolic blood pressure
(mmHg) |
112.4 ± 11.5 | 114.9 ± 9.8 | 114.9 ± 8.4 | 117.1 ± 10.0 |
|
Diastolic blood
pressure (mmHg) |
69.2 ± 8.6 | 72.8 ± 8.2 | 71.3 ± 4.7 | 72.7 ± 7.2 |
| FST triglyceride (mmol/L) | 1.1 ± 0.6 | 1.4 ± 0.8 | 1.2 ± 0.6 | 1.2 ± 0.6 |
|
FST total
cholesterol (mmol/L) |
3.9 ± 0.7 | 4.2 ± 0.7 | 4.3 ± 0.9 | 4.1 ± 0.9 |
|
FST
HDL-cholesterol (mmol/L) |
1.02 ± 0.19 | 1.14 ± 0.29 | 1.20 ± 0.24 | 1.18 ± 0.35 |
| FST glucose (mmol/L) | 5.02 ± 0.37 | 4.96 ± 0.31 | 4.98 ± 0.34 | 5.03 ± 0.35 |
| FST insulin (pmol/L) | 88.2 ± 37.5 | 83.3 ± 23.6 | 79.2 ± 20.8 | 90.3 ± 37.5 |
| MSRF | 1.2 ± 1.0 | 0.9 ± 0.8 | 0.7 ± 1.0 | 1.1 ± 1.0 |
| FST AST (U/L) | 23.1 ± 8.4 | 25.3 ± 8.5 | 22.1 ± 5.2 | 22.1 ± 5.6 |
| FST ALT (U/L) | 23.4 ± 20.1 | 22.2 ± 5.9 | 20.6 ± 8.1 | 21.5 ± 8.9 |
1 Values are mean ± SD; HFCS, high fructose corn syrup; FST, fasting; MSRF, metabolic syndrome risk factor; AST, aspartate aminotransferase; ALT, alanine aminotransferase.