Table 1.
Non-Exacerbation (N = 168) |
Exacerbation (N = 183) |
p-Value | |
---|---|---|---|
Gender | |||
Male | 73 (43.5%) | 69 (37.7%) | 0.324 |
Female | 95 (56.5%) | 114 (62.3%) | |
Age (years) | |||
Mean (SD) | 9.40 (1.83) | 8.89 (1.88) | 0.0109 |
Median [Min, Max] | 9.29 [4.50, 13.3] | 8.65 [0.271, 13.0] | |
Height (cm) | |||
Mean (SD) | 133 (15.7) | 131 (11.7) | 0.161 |
Median [Min, Max] | 133 [0, 163] | 129 [108, 167] | |
Weight (kg) | |||
Mean (SD) | 34.2 (12.2) | 31.4 (11.1) | 0.0245 |
Median [Min, Max] | 30.9 [15.0, 71.7] | 27.9 [17.0, 81.6] | |
BMI | |||
Mean (SD) | 18.6 (4.35) | 17.8 (3.56) | 0.0634 |
Median [Min, Max] | 17.2 [11.3, 41.4] | 16.8 [12.7, 34.0] | |
% Predicted Pre-BD FEV1 | |||
Mean (SD) | 98.6 (15.1) | 100 (17.1) | 0.423 |
Median [Min, Max] | 97.5 [53.1, 144] | 99.6 [46.2, 180] | |
% Predicted Pre-BD FVC | |||
Mean (SD) | 101 (15.3) | 104 (16.0) | 0.0662 |
Median [Min, Max] | 99.0 [52.5, 151] | 102 [54.6, 174] | |
FEV1/FVC pre-bronchodilator | |||
Mean (SD) | 87.5 (7.60) | 85.6 (7.99) | 0.0283 |
Median [Min, Max] | 87.5 [65.3,100] | 86.0 [61.8,99.9] | |
FEV1/FVC post-bronchodilator | |||
Mean (SD) | 89.9 (6.02) | 88.2 (7.07) | 0.0179 |
Median [Min, Max] | 89.4 [67.0,100] | 89.2 [66.4,100] | |
Bronchodilator Response as % of baseline FEV1 | |||
Mean (SD) | 4.38 (8.47) | 6.37 (9.57) | 0.0405 |
Median [Min, Max] | 2.88 [−15.3,48.6] | 5.10 [−16.3,47.2] | |
Inhaled Steroids | |||
No | 88 (52.4%) | 70 (38.3%) | 0.0108 |
Yes | 80 (47.6%) | 113 (61.7%) | |
Total IgE | |||
Mean (SD) | 1.79 (0.408) | 1.81 (0.391) | 0.596 |
Median [Min, Max] | 2.00 [1.00,2.00] | 2.00 [1.00,2.00] | |
Eosinophil Count | |||
Mean (SD) | 1.40 (0.491) | 1.51 (0.501) | 0.0444 |
Median [Min, Max] | 1.00 [1.00,2.00] | 2.00 [1.00,2.00] |
% predicted Pre-BD FEV1: Percent predicted pre-bronchodilator forced expiratory volume in one second. % predicted Pre-BD FVC: Percent predicted pre-bronchodilator forced vital capacity. % predicted FEV1/FVC post-BD: Percent predicted post-bronchodilator FEV1/FVC ratio. BD Response: Bronchodilator response as a percentage of pre-bronchodilator FEV1. Inhaled steroids: respondents indicating use of inhaled corticosteroids in previous year.