Table 5.
Statistically significant results of the DeSeq2 output comparing HLA-B27+ healthy offspring to HLA-B27+ SpA subjects. The full dataset is shown as Supplemental data. Abbreviations: LFC, log2Fold change; LFCSE, log2Fold change standard error; padj, adjusted (corrected) p-value. LFC values > 0 represent OTUs higher than the SpA subjects.
| Organism | BaseMean | LFC | LFCSE | padj |
|---|---|---|---|---|
| Bacteroides | 3233 | 1.27 | 0.47 | 0.047 |
| Blautia | 1803 | 1.47 | 0.35 | <0.001 |
| Bacteroides ovatus | 1132 | 1.12 | 0.40 | 0.040 |
| Faecalibacterium prausnitzii | 618 | −1.19 | 0.38 | 0.018 |
| Escherichia coli | 277 | 2.59 | 0.78 | 0.011 |
| Parabacteroides | 274 | 2.92 | 1.03 | 0.040 |
| Bifidobacterium | 128 | −2.12 | 0.59 | 0.004 |
| Coprococcus | 109 | −1.95 | 0.51 | 0.002 |
| Ruminococcus | 89 | −26.0 | 2.47 | <0.001 |
| Ruminococcus torques | 78 | 2.96 | 0.62 | <0.001 |
| Unspecified Lachnospiraceae | 67 | −2.12 | 0.76 | 0.047 |
| Coprococcus | 53 | −2.22 | 0.49 | <0.001 |
| Bacteroides | 50 | 3.01 | 0.97 | 0.018 |
| Unspecified Clostridiales | 46 | −10.8 | 2.44 | <0.001 |
| Unspecified Christensenellaceae | 43 | −5.96 | 2.01 | 0.043 |
| Bacteroides eggerthii | 27 | 4.49 | 0.89 | <0.001 |
| Ruminococcus | 20 | −24.2 | 2.94 | <0.001 |
| Bacteroides plebeius | 14 | −9.59 | 2.94 | 0.013 |
| Eubacterium biforme | 11 | −24.1 | 2.94 | <0.001 |
| Parabacteroides | 10 | 2.55 | 0.94 | 0.047 |
| Coprococcus eutactus | 6.6 | −5.87 | 1.81 | 0.013 |