Table 1.
Baseline information sheet for AMBN, assessing the difference in the composition ratios of the high and low AMBN mRNA expression subgroups in the different TGCT clinical variables.
| Characteristics | Total (N) | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|---|
| Hazard Ratio (95% CI) | p Value | Hazard Ratio (95% CI) | p Value | ||
| AMBN | 139 | 1.590 (0.468–5.400) | 0.458 | ||
| Pathologic stage | 132 | ||||
| Stage I | 106 | Reference | |||
| Stage II & Stage III | 26 | 0.210 (0.064–0.691) | 0.010 | 11,576,935.157 (1,535,060.618–87,309,534.264) | <0.001 |
| Clinical stage | 130 | ||||
| Stage I | 98 | Reference | |||
| Stage II & Stage III | 32 | 0.202 (0.071–0.576) | 0.003 | 0.000 (0.000–0.000) | <0.001 |
| Radiation therapy | 137 | ||||
| No | 113 | Reference | |||
| Yes | 24 | 0.873 (0.386–1.978) | 0.745 | ||
| Primary therapy outcome | 88 | ||||
| PR & PD | 14 | Reference | |||
| CR | 74 | 9.339 (1.264–68.994) | 0.029 | 155,601,452.260 (0.000–Inf) | 0.997 |
| Race | 134 | ||||
| Asian | 4 | Reference | |||
| Black or African American | 6 | 5.045 (0.520–48.936) | 0.163 | 6,123,473,977.844 (714,602,666.954–52,472,423,195.932) | <0.001 |
| White | 124 | 1.192 (0.163–8.728) | 0.863 | 246,966,750.563 (28,820,747.782–2,116,273,191.320) | <0.001 |
| Age | 139 | ||||
| <=30 | 67 | Reference | |||
| >30 | 72 | 0.697 (0.373–1.301) | 0.257 | ||
| Serum tumor markers(S) | 125 | ||||
| S0 | 43 | Reference | |||
| S1 | 41 | 1.944 (0.782–4.835) | 0.153 | 3.655 (1.527–8.750) | 0.004 |
| S2 | 36 | 2.908 (1.190–7.106) | 0.019 | 5.402 (2.230–13.087) | <0.001 |
| S3 | 5 | 3.993 (0.827–19.283) | 0.085 | 1.000 (1.000–1.000) | |
| Lymphovascular invasion | 135 | ||||
| No | 79 | Reference | |||
| Yes | 56 | 1.364 (0.733–2.538) | 0.327 | ||
| Testicular intratubular germ cell neoplasia | 130 | ||||
| Absent | 71 | Reference | |||
| Present | 59 | 0.729 (0.383–1.386) | 0.335 | ||
| History of undescended testis | 132 | ||||
| No | 109 | Reference | |||
| Yes | 23 | 0.560 (0.219–1.434) | 0.227 | ||
| Family history of testicular cancer | 122 | ||||
| No | 107 | Reference | |||
| Yes | 15 | 3.009 (1.407–6.435) | 0.005 | 1.637 (0.621–4.314) | 0.319 |
| Laterality | 134 | ||||
| Left | 74 | Reference | |||
| Right | 60 | 1.231 (0.639–2.371) | 0.534 | ||
| Pathologic T stage | 138 | ||||
| T1 | 80 | Reference | |||
| T2 & T3 | 58 | 1.158 (0.621–2.160) | 0.645 | ||
| Pathologic N stage | 64 | ||||
| N0 | 51 | Reference | |||
| N1 & N2 | 13 | 0.108 (0.015–0.793) | 0.029 | 1.000 (0.133–7.542) | 1.000 |
| Pathologic M stage | 124 | ||||
| M0 | 120 | Reference | |||
| M1 | 4 | 0.000 (0.000–Inf) | 0.996 | ||
| Clinical T stage | 118 | ||||
| T1 | 68 | Reference | |||
| T2 & T3 | 50 | 0.832 (0.433–1.596) | 0.579 | ||
| Clinical N stage | 113 | ||||
| N0 | 83 | Reference | |||
| N1 & N2 & N3 | 30 | 0.212 (0.074–0.608) | 0.004 | 1.000 (0.133–7.542) | 1.000 |
| Clinical M stage | 133 | ||||
| M0 | 125 | Reference | |||
| M1 | 8 | 0.624 (0.150–2.600) | 0.517 | ||