Table 3.
The change of bone mineral density or trabecular bone score among the patients who continued to the medication.
| No Medication | Bisphosphonate Usage | Teriparatide Usage | p | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Before | After | BMD Change |
BMD% Change |
Before | After | BMD Change |
BMD% Change |
Before | After | BMD Change |
BMD% Change |
||
| Bone mineral density of the lumbar spine | 1.02 (0.19) | 1.04 # (0.19) | 0.011 † (0.031) | 1.102 (3.155) †‡ |
0.80 (0.20) | 0.84 # (0.21) | 0.043 (0.045) | 5.573 (5.740) |
0.80 (0.17) | 0.84 # (0.16) | 0.036 (0.033) | 5.336 (5.360) |
0.001 <0.0001 |
| Bone mineral density of the whole femur | 0.83 (0.15) | 0.83 (0.16) | −0.003 (0.055) | −0.308 (6.655) |
0.69 (0.11) | 0.69 (0.11) | −0.007 (0.039) | −0.964 (5.881) |
0.70 (0.12) | 0.72 # (0.13) | 0.016 (0.019) | 2.261 (3.064) |
0.420 0.373 |
| Bone mineral density of the femoral neck | 0.68 (0.15) | 0.68 (0.14) | −0.002 ‡ (0.034) | −0.114 (5.315) ‡ |
0.54 (0.10) | 0.54 (0.10) | −0.0006 (0.025) ‡ |
0.142 (4.833) ‡ |
0.55 (0.11) | 0.57 # (0.11) | 0.027 (0.016) | 5.113 (3.115) |
0.020 0.011 |
| Trabecular bone score (n = 87) | 1.35 (0.10) |
1.34 (0.09) |
−0.007 (0.051) |
1.29 (0.09) |
1.23 (0.27) |
−0.060 (0.264) |
1.26 (0.08) |
1.29 (0.07) |
0.027 (0.051) |
0.205 | |||
p values determined by one-way analysis of variance for continuous variables and chi-squared test for categorical variables. For p value, the upper represents the difference of BMD change, and the lower represents the difference of BMD% change. The differences among three groups were determined by the Tukey HSD test: †, p < 0.05 versus bisphosphonate; ‡, p < 0.05 versus teriparatide. The differences of BMD and TBS between before and after were determined by the paired t-test: #, p < 0.05.