Table 3.
Treatment with potentially inappropriate medications with a risk of cognitive impairment (PIMcogn), in NH residents with and without registered dementia diagnosis, respectively.
| PIMcogn | Total, N (%) |
Dementia-diagnosis, n (%) |
No dementia-diagnosis, n (%) |
p-Value | |
|---|---|---|---|---|---|
| N = 574 | n = 523 | n = 45 | |||
| Glucocorticoids1 | 24 (4.2) | 21 (4.0) | 3 (6.7) | 0.426 | |
| Opioids | Regular and as needed treatment | 153 (26.7) | 135 (25.8) | 17 (37.8) | 0.082 |
| Regular treatment | 103 (17.9) | 89 (17.0) | 13 (28.9) | 0.046 | |
| Antiepileptics1 | 42 (7.3) | 35 (6.7) | 7 (15.6) | 0.029 | |
| Dopaminergic agents1 | 13 (2.3) | 11 (2.1) | 1 (2.2) | 1.000 | |
| Antipsychotics1 | 113 (19.7) | 107 (20.5) | 5 (11.1) | 0.171 | |
| Benzodiazepine derivatives | Regular and as needed treatment | 338 (58.9) | 308 (58.9) | 26 (57.8) | 0.884 |
| Regular treatment | 174 (30.3) | 158 (30.2) | 13 (28.9) | 0.853 | |
| Drugs with significant anticholinergic effects1 | 75 (13.1) | 65 (12.4) | 8 (17.8) | 0.304 | |
The level of statistical significance was set at p < 0.05.
1
Any treatment (i.e. regular and as needed treatment).