Table 1.
Dysregulated proteins between PCa patients and cancer-free subjects (Proteome Discoverer).
| Uniprot ID | Protein Name | Gene Name | p-Value | Cohen’s d [Lower; Upper 95% CI] |
|---|---|---|---|---|
| P07288 | Prostate-specific antigen | KLK3 | 0.00 | 4.21 (3.50; 4.91) |
| Q8WVN6 | Secreted and transmembrane protein 1 | SECTM1 | 0.01 | −2.16 (−2.39; −1.93) |
| P12830 | Cadherin-1 | CDH1 | 0.03 | −1.73 (−2.05; −1.41) |
| P0DOX5 | Immunoglobulin gamma-1 heavy chain | N/A | 0.03 | 1.73 (1.39; 2.07) |
| Q12805 | EGF-containing fibulin-like extracellular matrix protein 1 | EFEMP1 | 0.03 | −1.68 (−2.25; −1.12) |
| P02766 | Transthyretin | TTR | 0.03 | 1.66 (0.86; 2.46) |
| P01861 | Immunoglobulin heavy constant gamma 4 | IGHG4 | 0.04 | 1.52 (0.90; 2.15) |
| P01034 | Cystatin-C | CST3 | 0.05 | 1.50 (0.91; 2.08) |
| Q01459 | Di-N-acetylchitobiase | CTBS | 0.05 | −1.44 (−1.86; −1.02) |
The protein identification and label-free quantification performed by the Proteome Discoverer software revealed nine dysregulated proteins (p-value ≤ 0.05) between the tested groups. These proteins are shown in this table along with their p-value and effect size. The Cohen’s d for individual proteins is presented together with the lower and upper 95% confidence interval (CI). Abbreviation: Confidence interval (CI).