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. 2022 Apr 16;10(4):195. doi: 10.3390/toxics10040195

Figure 5.

Figure 5

The estimated EC50 isobole of Cu and Zn in comparison to two red dots showing synergistic toxic effects. The straight line of isobole is constructed using the EC50 values of Zn and Cu estimated from the results of single heavy metal experiments. Equation (4) was used to obtain two red dots from the results of a combination of two HM experiments.