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. 2022 Mar 28;10(4):786. doi: 10.3390/biomedicines10040786

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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lnc-IL7R positively correlates with physiological pulmonary function and exhibits diagnostic relevance for COPD-based patient stratification. (A) Visualization of principal component analysis based on factor analysis loading showing the associative predisposition of our panel of COPD-related variables and their stratification into components 1 and 2. (B) Correlative heat map of our panel of COPD-related variables. (C) Ellipsoid 3D image of the association between lnc-IL7R, GOLD-defined COPD severity, and %LAA_-950insp-based Emphysema severity. (D) Graphical depiction of the ROC curve and AUC value of lnc-IL7R expression in our COPD cohort. (E) Statistical chart of the ROC curve of lnc-IL7R expression. ROC, receiver operating characteristic; AUC, area under curve.