Table 1.
Demographic and clinical characteristics of TBE and TBE co-infected (TBE+LD) patients compared to healthy subjects (CTR, control).
| CTR | TBE | TBE+LD | |
|---|---|---|---|
| Age (years) | 40.25 ± 7.42 | 42.75 ± 9.33 | 42.5 ± 15.24 |
| Sex, female/male |
4/8 female (50%) 4/8 male (50%) |
7/16 female (43%) 9/16 male (57%) |
3/5 female (60%) 2/5 male (40%) |
| Place of residence (urban/rural area) |
7/16 urban (44%) 10/16 rural (56%) |
3/5 urban (60%) 2/5 rural (40%) |
|
| Noticeable tick bite | 0/8 (0%) | 9/16 (56%) | 5/5 (100%) |
| Time since tick bite (days) | 25 ± 16.19 | 17.5 ± 4.95 | |
| Duration of hospitalization (days) | 12.56 ± 2.13 | 12.6 ± 2.07 | |
| Duration of symptoms (days) | 8.53 ± 8.08 | 4.33 ± 3.21 | |
| Clinical form | |||
| Meningitis | 0/8 (0%) | 10/16 (62%) | 4/5 (83%) |
| Meningoencephalitis | 0/8 (0%) | 6/16 (38%) | 1/5 (17%) |
| Meningoencephalomyelitis | 0/8 (0%) | 0/16 (0%) | 0/5 (0%) |
| Clinical presentation | |||
| Headache | 0/8 (0%) | 16/16 (100%) | 5/5 (100%) |
| Fever | 0/8 (0%) | 15/16 (94%) | 4/5 (80%) |
| Neck stiffness | 0/8 (0%) | 13/16 (81%) | 3/5 (60%) |
| Kernig’s sign | 0/8 (0%) | 5/16 (31%) | 1/5 (20%) |
| Vertigo | 0/8 (0%) | 7/16 (44%) | 0/5 (0%) |
| Nausea | 0/8 (0%) | 7/16 (44%) | 2/5 (40%) |
| Vomiting | 0/8 (0%) | 6/16 (38%) | 0/5 (0%) |
| Ataxia | 0/8 (0%) | 5/16 (31%) | 0/5 (0%) |
| Tremor | 0/8 (0%) | 4/16 (25%) | 0/5 (0%) |
| Hyperesthesia | 0/8 (0%) | 2/16 (13%) | 1/5 (20%) |
| Muscle pain | 0/8 (0%) | 1/16 (6%) | 0/5 (0%) |
| Joint pain | 0/8 (0%) | 1/16 (6%) | 0/5 (0%) |
| Consciousness disturbances | 0/8 (0%) | 1/16 (6%) | 0/5 (0%) |
| Skin lesion | 0/8 (0%) | 0/16 (0%) | 1/5 (20%) |
| Muscle weakness | 0/8 (0%) | 0/16 (0%) | 1/5 (20%) |