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. 2022 Apr 18;11(4):613. doi: 10.3390/biology11040613

Figure 6.

Figure 6

The kinetics of decay and the time for activation of resurgent Na+ currents in the WT, p.V781I, and p.A1737T channels. (A) The reciprocal of decay time constants (1/tau) of the resurgent Na+ currents obtained at −60 mV after the depolarizing prepulse between +40 and +180 mV in 20 mV increments for approximately 10 ms in the WT and the p.V781I, and p.A1737T mutant channels (n = 8). (B) With different prepulse voltages, the time to peak to generate resurgent Na+ current was faster in the WT channel than in the p.V781I and p.A1737T mutant channels. (n = 8 *; p < 0.05).