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Analysis of oral HPV prevalence by sex. (A) Prevalence of oral HPV significantly increased among pediatric males (40.4%) between 2012 and 2019, p = 0.0018, with higher increases (93.9%) observed among pediatric females over the same interval, p = 0.00013. (B) Oral HPV among adult males increased more than 5.3-fold, p = 0.0001, between 2011 and 2018, with more than 9.5-fold increases observed among adult females during the same time period, p = 0.00001.
