Table 3.
Force and AUC of injectability, and adhesion properties of the vancomycin HCl-loaded rosin-based ISG and ISM formulations (n = 3).
| Formula | Injectability Force (N) |
Injectability AUC (N.s) |
Adhesion Properties | |||
|---|---|---|---|---|---|---|
| Maximum Force (N) |
Adhesion Force (N) |
Remaining Force (N) |
Elastic Properties | |||
| 20RV | 1.10 ± 0.01 | 20.59 ± 0.42 | 3.786 ± 0.172 | −0.026 ± 0.010 | 1.364 ± 0.244 | 0.36 |
| 30RV | 2.73 ± 0.12 | 37.89 ± 2.24 | 3.579 ± 1.170 | −0.002 ± 0.001 | 2.123 ± 0.773 | 0.59 |
| 40RV | 3.10 ± 0.04 | 56.19 ± 0.57 | 0.856 ± 0.065 * | −0.050 ± 0.001 * | 0.057 ± 0.026 | 0.07 |
| 50RV | 7.98 ± 0.17 | 140.48 ± 5.29 | 0.737 ± 0.084 * | −0.051 ± 0.001 * | 0.052 ± 0.003 | 0.07 |
| 60RV | - | - | 0.420 ± 0.043 * | −0.053 ± 0.002 * | 0.026 ± 0.005 | 0.06 |
| 40RV ISM | 5.36 ± 0.02 | 92.24 ± 2.58 | 1.227 ± 0.329 * | −3.4658 ± 0.517 * | 1.128 ± 0.350 | 0.91 |
| 50RV ISM | 8.31 ± 0.73 | 135.32 ± 3.75 | 0.133 ± 0.077 * | −2.010 ± 0.525 * | 0.003 ± 0.002 | 0.03 |
| 60RV ISM | 16.83 ± 1.14 | 272.89 ± 17.69 | 0.060 ± 0.016 * | −0.192 ± 0.019 * | 0.005 ± 0.001 | 0.08 |
* indicate a significant difference at 95% confidential interval between ISG and ISM maximum and adhesion force in adhesion properties by using independent t-test analysis.