Table 2.
Summary of dose volume histogram parameters and changes of lymphocytes during neoadjuvant chemoradiotherapy between Groupphoton and Groupproton.
| Variables | Groupphoton (n = 16) | Groupproton (n = 15) | p-Value |
|---|---|---|---|
| Total dose, Gy (median, range) | 41.4 Gy (26.0–50.4) | 41.4 Gy (37.8–50.0) | 0.705 |
| Lung mean, cGy (mean ± SD) | 816.00 ± 251.63 | 431.27 ± 189.35 | <0.001 |
| Lung V10, % (mean ± SD) | 23.65 ± 10.23 | 14.23 ± 6.21 | 0.005 |
| Lung V20, % (mean ± SD) | 13.31 ± 5.53 | 9.07 ± 3.87 | 0.02 |
| Heart mean, cGy (mean ± SD) | 2774.88 ± 651.92 | 1410.80 ± 615.92 | <0.001 |
| Heart V10, % (mean ± SD) | 80.46 ± 13.68 | 55.11 ± 24.54 | 0.001 |
| Heart V30, % (mean ± SD) | 51.89 ± 21.31 | 18.35 ± 8.89 | <0.001 |
| Heart V40, % (mean ± SD) | 35.43 ± 25.85 | 12.55 ± 6.40 | 0.003 |
| Grade 4 lymphopenia (n, %) | 2 (12.5%) | 3 (20.0) | 0.654 |
| Lymphocyte count nadir (mean ± SD) | 396.49 ± 156.48 | 388.02 ± 239.22 | 0.907 |