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. 2022 Apr 8;14(8):1879. doi: 10.3390/cancers14081879

Figure 2.

Figure 2

Changes in PROs from enrolment at week 6 and 12: (A) MDASI symptom severity, (B) MDASI interference, (C) EQ-5D (UK) Index, (D) EQ-VAS. Each of the 13 symptoms in the MDASI symptom severity scale is rated on an 11-point scale to indicate the presence and severity of the symptom in the last 24 h with 0 meaning ‘not present’ and 10 meaning ‘as bad as you can imagine’. Each of the 6 items in the MDASI symptom interference scale is rated based on the level of symptom interference with the function of a patient’s life in the last 24 h and also measured on an 11-point scale (0 = ‘did not interfere’ to 10 = ‘interfered completely’). The EQ-5D-3L descriptive system comprises 5 dimensions and each dimension is rated based on 3 levels: no problems, some problems, extreme problems. The EQ-VAS records the respondent’s self-rated health on a vertical, visual analog scale (gradated from 0–100) where the endpoints are labeled ‘Best imaginable health state’ and ‘Worst imaginable health state’ with higher scores indicating higher HRQoL.EQ-5D—EuroQoL 5-Dimensions; MDASI—M.D. Anderson Symptom Inventory; N—number of patients; PRO—patient-reported outcome; SD—standard deviation; UK—United Kingdom; VAS—Visual Analogue Scale.