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. 2022 Apr 14;14(8):1641. doi: 10.3390/nu14081641

Table 2.

Biomarkers related to COVID-19 severity.

Severe COVID-19, Including Death
(n = 105)
Non-Severe COVID-19
(n = 123)
p Value **
CRP (mg/L) * 179 (111–271)
(n = 104)
81 (46–140)
(n = 122)
<0.001
LDH (U/L) * 352 (269–488)
(n = 23)
240 (198–281)
(n = 27)
<0.001
Leukocyte (giga/L) * 15.5 (11.4–19.1)
(n = 105)
9.25 (7.10–11.61)
(n = 121)
<0.001
Neutrophilic polynuclear (giga/L) * 12.6 (9.21–15.5)
(n = 105)
7,09 (4.78–9.24)
(n = 121)
<0.001
Lymphocyte (giga/L) * 0.5 (0.41–0.77)
(n = 105)
0.77 (0.54–1.16)
(n = 121)
<0.001
Platelets (giga/L) * 422 (330–541)
(n = 105)
353 (284–450)
(n = 121)
0.003
Fibrinogen (g/L) * 7.61 (6.32–9.17)
(n = 103)
5.41 (4.08–7.14)
(n = 104)
<0.001
D-dimer (μg/L) * 1879 (1136–5123)
(n = 93)
1170 (673–2407)
(n = 58)
0.004
Albumin (g/L) * 19.7 (16–23.9)
(n = 98)
28.5 (25.4–32.8)
(n = 119)
<0.001

Abbreviations: IQR, interquartile range; CRP, C-reactive protein; LDH, Lactate dehydrogenase. * Maximum values during hospitalisation for CRP, LDH, D-dimer, leukocyte, neutrophilic polynuclear, and platelets counts. Minimum values for lymphocyte count and albumin. ** Mann–Whitney U test.