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. 2022 Mar 29;20(4):233. doi: 10.3390/md20040233

Figure 2.

Figure 2

Comparison of VGSC binding vs. THP-1 cytotoxicity for the four brevetoxin B analogs. A receptor binding assay was used to measure binding of brevetoxins to the VGSC receptor (Panel A), whereas an XTT assay was used to measure cytotoxicity of the brevetoxins to THP-1 monocytes (Panel B). Black squares indicate PbTx-2, green circles indicate PbTx-3, red diamonds indicate PbTx-6, and blue triangles indicate BTX-B5. Data are shown as mean +/− standard deviation for each concentration (n = 3 for each assay).