Table 1.

Weight changes due to side effects of TMZ treatment. Values are expressed as means ± standard deviations (SDs). ns: not significant.

Average Body Weight (g)
Group	Non-treatment	TMZ-40 mg	TMZ-60 mg
Day 7	198.2 ± 14.9	194.1 ± 12.1	211.9 ± 7.4
Day 14	224.1 ± 13.0	189.7 ± 16.4	204.3 ± 10.4
Average body weight ratio
Day 14/Day 7	1.13	0.98	0.96
Compared groups		p
Non-treatment	TMZ-40 mg	<0.0001
Non-treatment	TMZ-60 mg	<0.0001
TMZ-40 mg	TMZ-60 mg	ns

ns: not significant.