Table 2.
Differences in the median white blood cell (WBC) count and leukocyte and main lymphocyte subpopulation counts between patients with COVID-19 and convalescent COVID-19 patients. Data expressed as median (Q1–Q3). A * marks statistical significance at p < 0.05 (Mann–Whitney U test).
| WBC and Study Subpopulation [k/µL] |
Patients with COVID-19 Median (Q1–Q3) |
Convalescent Median (Q1–Q3) |
* p < 0.05 Mann–Whitney U Test |
|---|---|---|---|
| WBC | 7000 (4640–9020) | 7930 (6600–10,470) | * 0.024360 |
| Lymphocytes | 1025 (710–1570) | 1662 (1170–2199) | * 0.000014 |
| T Lymphocytes | 680 (422–1103) | 1271 (826–1607) | * 0.000005 |
| CD4 cells | 461 (271–675) | 775 (559–1117) | * 0.000047 |
| CD8 cells | 204 (130–403) | 439 (238–567) | * 0.000133 |
| Ratio CD4/CD8 | 2.0 (1.3–2.9) | 2.1 (1.2–2.8) | 0.825576 |
| B Lymphocytes | 120 (64–216) | 172 (120–281) | * 0.016123 |
| NK cells | 146 (79–253) | 178 (74–300) | 0.434570 |
| Neutrophils | 5143 (3192–7941) | 5319 (4135–7581) | 0.457164 |
| Eosinophils | 8 (0–38) | 72 (18–190) | * 0.000006 |
| Basophils | 9 (4–21) | 24 (8–54) | * 0.005186 |
| Monocytes | 377 (260–454) | 536 (399–815) | * 0.000020 |
| % of all leukocytes | |||
| Lymphocytes | 14,7 (9.1–28.2) | 22.4 (12.8–30.5) | * 0.044030 |
| T Lymphocytes | 10.5 (5.5–20.7) | 16.9 (8.9–22.2) | * 0.013242 |
| CD4 cells | 5.6 (3.5–13.3) | 10.5 (5.4–14.7) | * 0.016998 |
| CD8 cells | 3.5 (1.8–6.1) | 4.9 (3.4–7.1) | * 0.046088 |
| B Lymphocytes | 1.7 (1.0–2.6) | 2.1 (1.4–3.2) | 0.225750 |
| NK cells | 2.5 (1.1–4.1) | 2.0 (1.0–3.9) | 0.492249 |
| Neutrophils | 79.4 (63.4–86.9) | 68.8 (60.1–79.1) | * 0.015562 |
| Eosinophils | 0.1 (0.0–0.8) | 1.1 (0.2–2.4) | * 0.000093 |
| Basophils | 0.1 (0.1–0.3) | 0.3 (0.1–0.6) | 0.060189 |
| Monocytes | 5.5 (3.8–7.6) | 7.0 (4.6–9.1) | * 0.037130 |
Abbreviation: WBC: white blood count.