Table 4.
Overview of differences in biomarker levels between patients with SARS-CoV-2 infection who were admitted to hospital (Groups 2–4) and patients with SARS-CoV-2 infection who were discharged (Group 1).
| Biomarker | Number of Samples | Biomarker Level (log2), Median (IQR) | Median Difference | p-Value | AUC (95% CI) |
||||
|---|---|---|---|---|---|---|---|---|---|
| Admitted | Discharged | Total | Admitted | Discharged | Total | ||||
| CRP | 444 | 73 | 517 | 3.46 (2.21, 4.23) |
1.33 (−1.15, 3.03) |
3.26 (1.85, 4.14) |
2.131 | <0.001 | 0.775 (0.718, 0.832) |
| GDF-15 | 410 | 90 | 500 | 11.45 (10.90, 12.30) |
10.97 (9.76, 12.02) |
11.39 (10.78, 12.25) |
0.485 | <0.001 | 0.625 (0.551, 0.699) |
| IL-6 | 471 | 96 | 567 | 5.85 (4.93, 6.78) |
3.79 (2.24, 5.12) |
5.56 (4.51, 6.64) |
2.059 | <0.001 | 0.800 (0.750, 0.851) |
| sACE2 | 479 | 112 | 591 | −4.64 (−5.06, −2.32) |
−2.64 (−4.73, −0.91) |
−4.06 (−5.06, −2.00) |
−2.000 | <0.001 | 0.648 (0.592, 0.704) |
| sFlt-1 | 410 | 90 | 500 | 6.96 (6.66, 7.24) |
6.50 (6.23, 6.78) |
6.88 (6.56, 7.18) |
0.454 | <0.001 | 0.751 (0.689, 0.813) |