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. 2022 Apr 22;130(4):047006. doi: 10.1289/EHP10077

Figure 3.

Figure 3 is a set of eight error bar graphs titled mono-ethyl phthalate, mono-n-butyl phthalate, monobenzyl phthalate, mono-isobutyl phthalate, mono(3-carboxypropyl) phthalate, monocarboxyoctyl phthalate, monocarboxy-isononyl phthalate, summed di-2-ethylhexyl phthalate, plotting mean difference (95 percent confidence intervals) in body mass index lowercase z score, ranging from negative 0.4 to 0.4 in increment of 0.2 (y-axis) across birth, 1 year of age, 3 years of age, 4 years of age, and 6 years of age (x-axis), respectively.

Adjusted difference in BMI z-scores (95% CIs) per IQR increase in pregnancy average of individual phthalate metabolite biomarkers (n=738). Effect estimates were calculated using linear mixed-effects models adjusted for maternal age (y), race (White, Black, other), education level (high school or less/any technical school or college/graduate work), prepregnancy BMI (kg/m2), and study site (UCSF, UMN, URMC, UW). For the birth exam, weight-to-length ratio z-scores are presented instead of BMI z-scores. For models of MCOP and MCNP, n=729. No data was collected for females at 1 year of age. *, p<0.05 for overall association of phthalate metabolite on outcome based on likelihood ratio tests. Corresponding effect estimates are presented in Table S5. Note: BMI, body mass index; CI, confidence interval; IQR, interquartile ratio; MBP, mono-n-butyl phthalate; MBzP, monobenzyl phthalate; MCNP, monocarboxy-isononyl phthalate; MCOP, monocarboxyoctyl phthalate; MCPP, mono(3-carboxypropyl) phthalate; MEP, mono-ethyl phthalate; MiBP, mono-isobutyl phthalate; ΣDEHP, summed di-2-ethylhexyl phthalate; UCSF, University of California, San Francisco; UMN, University of Minnesota; URMC, University of Rochester Medical Center; UW, University of Washington.