TABLE 5.

Variability of IC_50^s of clinical isolates obtained from antiviral-naive patients^a

Drug	n	IC50 (μM)		Fold increaseb
		Mean ± SD	Range
AZT	22	0.04 ± 0.03	0.003–0.15	0.1–5
3TC	20	1.17 ± 0.90	0.1–3.2	0.12–3.86
d4T	21	2.36 ± 2.00	0.33–7.5	0.14–3.23
RTV	15	0.03 ± 0.02	0.01–0.08	0.33–2.67
SQV	16	0.02 ± 0.02	0.001–0.1	0.1–10
NFV	14	0.007 ± 0.009	0.001–0.03	0.3–10

^aAll assays were performed in triplicate. 

^bFold increase was calculated by dividing the IC₅₀ of each drug by the mean IC₅₀ for NL432 in each assay.