Figure 8.

Effects of TH1902 and carboplatin combinations on A2780 ovarian cancer xenografts. A2780 cells were subcutaneously implanted in the flanks of athymic nude mice. Tumor volume measurements following bi-weekly administrations of (A) vehicle, docetaxel, TH1902, paclitaxel or carboplatin as single agents, or (B) administered once in combination using the same dosage as described in the methods section. Colored dots below indicate drug treatments for all groups. Data are represented as mean ± SEM (n = 5 mice/group).