Activities on the 5-HT_2C, H₁ and α₁ receptors (K_i nM) of the candidate and reference antipsychotics.

Cmpd	Receptor affinity Ki ± SEMa (nM)			hERG IC50 (nM)
	5-HT2C	α1	H1
3t	430.4 ± 52.3	398.2 ± 49.5	668.3 ± 32.5	1158
3w	572.2 ± 91.5	405.5 ± 60.8	819.6 ± 48.7	1765
Risperidone	30.1 ± 2.8	51.4 ± 3.6	23.8 ± 1.5	1480

^a K _i values obtained from three experiments, recorded as means ± SEM.