In vivo pharmacological profile of the compounds.

Cmpd	LD50	APOa	MK-801b	CATc	CARd	CAT/APO	CAT/MK-801
3w	>1000	0.28	0.17	27.5	2.1	91.07	161.76
Haloperidol	21.0	0.09	0.11	0.12	—	5.67	4.63
Risperidone	82.0	0.05	0.02	0.51	0.65	10.4	32.5

^aAPO: apomorphine-induced climbing (ED₅₀, mg kg⁻¹, po (per os)).

^bMK-801: MK-801-induced hyperactivity (ED₅₀, mg kg⁻¹, po).

^cCAT: catalepsy (ED₅₀, mg kg⁻¹, po).

^dCAR: conditioned avoidance response (ED₅₀, mg kg⁻¹, po).