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. 2022 Apr 16;10(4):917. doi: 10.3390/biomedicines10040917

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Cd exposure induced rounding of nuclei. (A) Shapes of selected nuclei with various C/B ratios from ht-UTLM6 and CR-LM6 populations. The C/B ratio is defined as ratio between the length of the longest principal axis of a nucleus and the length of the second longest principal axis. Scale bar = 15 μm. (B) The distribution of C/B ratio in ht-UTLM6. The data labels shown on top of the bars are the absolute counts. (C) The distribution of C/B ratio in CR-LM6. (D) The overlay of inset B and inset C by probability density function. The x-axis is the C/B ratio and y-axis is probability density.