Figure 7.

Expression of CD23+ B cells in nasal mucosa. (A) Representative images of CD19+CD23+ expression in nasal mucosa detected by immunofluorescence staining (magnification 1000×). DAPI, the nuclear staining (blue). CD19, a specific marker for B lymphocytes (green). CD23, the low-affinity receptor for IgE (red). CD19+CD23+, double positive for CD19 and CD23 expression (yellow). Scale bars = 20 μm. (B) Statistical analysis of the percentages of CD19⁺CD23⁺ cells in the nasal mucosa. The AR group was sensitized with HDM challenge. The AR-SO₂-day15 group and AR-SO₂-day1 group included HDM-sensitized mice exposed to SO₂ beginning on day 15 and day 1, respectively. The NS group was challenged with normal saline instead of HDM. The SO₂-treated control group was challenged with normal saline and exposed to SO₂ beginning on day 1. The data are presented as the mean ± SEM. *p < 0.05 vs the NS group. ^#p < 0.05 vs the SO2-treated control group. ^ap < 0.05 vs the AR group. ^bp < 0.05 vs the AR-SO₂-day15 group.

Abbreviations: SO₂, sulfur dioxide; NS, normal saline; AR, allergic rhinitis.