FIG. 2.

Summary of mean values ± SD (error bars) for hypericin decay plots from patients receiving hypericin at 0.05 (n = 7) and 0.1 (n = 4) mg/kg who agreed to undergo detailed pharmacokinetic sampling. The decays were fitted with one-compartment model with a first-order absorption (nonlinear fit) and showed dose proportionality for the AUC determinations (1.5 versus 3.1 μg/ml × h, respectively, for 0.05- and 0.1-mg/kg dose levels).