TABLE 3.

Photosensitivity reactions experienced by subjects by dosage group^a

Photosensitivity reaction	No. of subjects in dosing group
	0.05 mg/kg (n = 12)	0.1 mg/kg (n = 7)
Paresthesias
Mild (grade 1)	5	3
Moderate (grade 2)	1	2
Severe (grade 3)	2b	0
Dermatitis
Mild (grade 1)	1	2
Moderate (grade 2)	1	0
Severe (grade 3)	0	0
Darkened coloration of exposed skin
Mild (grade 1)	0	3
Moderate (grade 2)	0	0
Severe (grade 3)	0	0
Pruritic nodules
Mild (grade 1)	0	1
Moderate (grade 2)	0	0
Severe (grade 3)	0	0

^aNote: All the photosensitivity reactions listed in Table 3 were judged to be probably related to hypericin. 

^bThe study medications were discontinued in these two patients.