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. 2022 Apr 9;14(8):1900. doi: 10.3390/cancers14081900

Figure 1.

Figure 1

Schematic of our chronic dust exposure mouse model and dosing timeline. Male and female A/J mice received 24 weeks of intranasal challenges of 12.5% HDE, a single i.p. injection of 100 mg/kg NNK to induce tumorigenesis, and a once weekly tail i.v. of 500 ng AT-RvD1 for 21 weeks.