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. 2022 Apr 9;14(8):1900. doi: 10.3390/cancers14081900

Figure 3.

Figure 3

Effects of chronic HDE exposure and AT-RvD1 treatment on BALF cytokine levels after 24 weeks. Bronchoalveolar lavage was performed at the end of the 24 weeks and the fluid was collected to assess cytokine levels as described in the methods. For IL-6 (A), IL-10 (B), and TGFβ-1 (C); n = 5–10 for saline only; n = 7–8 for HDE only; n = 6–7 for saline + NNK; n = 6–9 for HDE + NNK; n = 5–8 for saline + AT-RvD1; n = 5 for HDE + AT-RvD1; n = 5–6 for saline + NNK + AT-RvD1; n = 4–5 for HDE + NNK + AT-RvD1. Main significant effects and interactions from three-way ANOVA analysis are shown above each graph. The ** symbol above the HDE bar represents the statistical post hoc comparison to the saline control group; (** p < 0.01).