Figure 1.

Assessment of the cellular toxicity induced by trehalose, conjugates 1a and 1b and NAs 5a and 5b. We evaluated cell viability upon compound treatment by MTT. (A) Cytotoxicity assay on HeLa cells treated for 24 h with trehalose, squalene, 4,4’-dithiodibutyric acid (linker), 1b and 5b. Data are presented as mean ± SE; *** p < 0.001, ** p < 0.01, * p < 0.05 vs. trehalose, n = 10–15. (B) Cytotoxicity assay on HeLa cells treated for 24 h with trehalose, squalene, linker, 1a and 5a. Data are presented as mean ± SE * p < 0.05 vs. trehalose, n = 10–15.