| AEME | anhydroecgonine methyl ester |
| ATP | adenosine triphosphate |
| BBB | blood brain barrier |
| BE | benzoylecgonine |
| CE | cocaethylene |
| CNS | central nervous system |
| CUD | cocaine use disorder |
| CYP450 | cytochrome P450 |
| DAT | dopamine transporter |
| DSM-5 | Diagnostics and Statistics Manual of Mental Disorders 5th edition |
| EC | ecgonine |
| ED | ecgonidine |
| EDEE | ecgonidine ethyl ester |
| EEE | ecgonine ethyl ester |
| EMCDDA | European Monitoring Centre for Drug and Drug Addiction |
| EME | ecgonine methyl ester |
| FADM | flavin adenine dinucleotide-containing monooxygenase |
| GC-MS | gas chromatography coupled with mass spectrometry |
| GPx | glutathione peroxidase |
| GSH | reduced glutathione |
| hCE1 | human carboxylesterase type 1 |
| hCE2 | human carboxylesterase type 2 |
| HPLC | high performance liquid chromatography |
| LC-MS/MS | liquid chromatography coupled with tandem mass spectrometry |
| NAT | noradrenaline transporter |
| NBE | norbenzoylecgonine |
| NCE | norcocaethylene |
| NCOC | norcocaine |
| NCOC-NO• | orcocaine nitroxide |
| NCOC-NO+ | norcocaine nitrosonium |
| NEDME | norecgonidine methyl ester |
| NEME | norecgonine methyl ester |
| NMDA | N-methyl-D-aspartate |
| N-OH-NCOC | N-hydroxy-norcocaine |
| (p-/m-)OH-BE | (para-/meta-)hydroxybenzoylecgonine |
| (p-/m-)OH-COC | (para-/meta-)hydroxycocaine |
| PChE | pseudocholinesterase |
| ROS | reactive oxygen species |
| SERT | serotonin transporter |
| SOD | superoxide dismutase |
| UPLC-MS/MS | ultra-performance liquid chromatography coupled with tandem mass spectrometry |