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. 2022 Apr 7;9(4):164. doi: 10.3390/bioengineering9040164

Figure 7.

Figure 7

Conventional two-step lactide synthesis process (reprinted with permission [48], Copyright 2019 American Chemical Society): (1) lactic acid stream, (2) lactic acid + reflux mixed stream, (3) dehydrated lactic acid stream, (4) wastewater, (5) dehydrated lactic acid stream, (6) lactic acid recovery, (7) R-1 liquid phase, (8) catalyst feed stream, (9) lactic acid + catalyst mixed stream, (10) oligomers stream, (11) unreacted oligomers stream, (12) unreacted oligomer recovery, (13) high molar mass oligomers, (14) crude lactide stream, (15) purified lactide stream, (16) unpurified lactide stream, (C-1, C-2) distillation columns, (R-1, R-2) polycondensation and depolymerization reactors, respectively, (F-1, F-2) heating duties.