Table 2.
Perioperative and pathological data of patients undergoing operation for MEN1-ZES.
| Parameter | ALL (n = 35) |
PD (n = 11) |
Thompson (n = 12) |
DUODX (n = 12) |
p-Value PD vs. Non-PD * |
|---|---|---|---|---|---|
| Pts. with complications Dindo ≥ 3 | 12/35 (37%) | 4/11 (36%) | 3/12 (25%) | 5/12 (42%) | 0.433 |
| POPF Typ B | 1/35 (3%) | 1/11 (9%) | 0/12 | 0/12 | 0.341 |
| POPF Type C | 2/35 (6%) | 1/11 (9%) | 0/12 | 1/12 (8%) | 0.574 |
| Postoperative bleeding | 4/35 (11%) | 0/11 | 2/12 (17%) | 2/12 (17%) | 0.043 |
| Postoperative pancreatitis | 2/35 (6%) | 1/11 (9%) | 0/12 | 1/12 (8%) | 0.574 |
| Reoperation due to complications | 8/35 (20%) | 2/11 (18%) | 3/12 (17%) | 3/12 (25%) | 0.667 |
| Perioperative mortality | 0/35 | 0/11 | 0/12 | 0/12 | 1 |
| No. of pNENs in specimen (median/range) | 3 (0–18) | 4 (0–18) | 3 (1–7) | 1 (0–3) | 0.255 |
| No. duodenal gastrinomas (median/range) |
3 (1–13) | 3 (1–8) | 2 (1–13) | 3 (1–6) | 0.430 |
| No. resected lymph nodes (median/range) | 11 (3–25) | 15 (3–25) | 14 (8–20) | 9 (6–12) | 0.279 |
| Lymph node ratio (affected/analyzed) | 0.07 | 0.13 | 0.07 | 0.11 | 0.626 |
| Postop. normal serum gastrin (<125 pg/mL) | 30/35 (86%) | 10/11 (91%) | 10/12 (83%) | 10/12 (83%) | 0.566 |
| Postoperative Diabetes mellitus # | 0/35 | 0/11 | 0/12 | 0/12 | 1 |
pNEN = pancreaticoduodenal neuroendocrine neoplasm; PD = pancreaticoduodenectomy; DUODX + LAD = duodenotomy, excision of duodenal gastrinomas, and lymphadenectomy; POPF = postoperative pancreatic fistula; * non-PD includes both Thompson and DUODX resections; # in the first 30 postoperative days.