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. 2022 Mar 31;11(4):682. doi: 10.3390/antiox11040682

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of tlr22 knockdown on PA-induced inflammation in macrophages. (A) The mRNA expression of tlr22 after tlr22 knockdown. (B) Effects of tlr22 knockdown on the mRNA expression levels of inflammatory genes induced by PA. (C) Effects of tlr22 knockdown on the phosphorylation of the MAPK pathway induced by PA. The ratios of p-p38 to p38 and p-JNK to JNK were determined. The data are presented as the means ± SEM (n = 3) and are analyzed using independent t-tests. * p < 0.05 and ** p < 0.01 indicate significant differences compared with the control group.