Figure 2. 12/15LO and Id3 expressions in post-injury LCCAs are greater in 12/15LO-tg compared with BL-6 mice.
Male BL-6 and 12/15LO-tg mice were fed western diet starting at 10-12 weeks of age and underwent LCCA endothelial denudation one week later. LCCAs were harvested seven days and 14 days after the injury and 12/15LO (2A) and Id3 (2B) mRNA expressions were determined by real-time RT-PCR. Each dot represents mRNA expression of one mouse.