Passage 7-9 VSMCs from BL-6, 12/15LO-tg, Id3−/−, 12/15LO-tg/Id3−/−, ApoE−/−, and DKO mice were plated at the same density. By direct counting, the cell numbers quantified at twelve hours after plating (defined as baseline), and then every 24 hours x 4. Data is mean of four independent experiments. 4A: (#) p<0.05 for 12/15LO-tg vs. 12/15LO-tg/Id3−/−, (*) p<0.05 for 12/15LO-tg vs. BL-6. 4B: (*) p<0.05.