FIGURE 11 |.

The gyrification index is a measure for the degree of folding. Here, we compute a gyrification index for 164 coronal slices generated from our finite element model. We compare the gyrification index for the young brain, aged brain, and in Alzheimer’s disease and observe a noticeable decrease in Alzheimer’s disease in the temporal and parietal lobes while the frontal lobe, which is affected least in terms of atrophy, shows only small deviations. Peak gyrification is observed in the vicinity of the sylvian fissure which is widens significantly as discussed before.