TABLE 1 |.

Multiphysics atrophy model parameters which include Lamé constants, healthy and pathological atrophy rates, critical biomarker concentration, and biomarker spreading parameters for white matter, gray matter, the hippocampus, ventricles, and cerebrospinal fluid.

	Lamé constants		Atrophy model parameters			Biomarker model parameters
	λ [kPa]	μ [kPa]	Gh [−]	Gc [-−]	ccrit [−]	d [W/kg m3]	α [−]
White matter	64.67	2	0.0015	0.0035	0.5	15	0.09
Gray matter	32.33	1	0.001	0.002	0.5	15	0.09
Hippocampus	32.33	1	0.001	0.002	0.5	15	0.09
Ventricles	29.77	15.34	—	—	—	0	0.09
CSF	7.22	14.43	—	—	—	0	0.09