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. 2022 Apr 4;14(4):788. doi: 10.3390/pharmaceutics14040788

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Scratch-wound migration assay. (A) Snapshots of the scratch-wound area of MDA-MB-231 cells treated with DMSO, JE22, Naked-NPs (1), and JE22-NPS (5) at time zero (top) and after 24 h (bottom). White lines highlight the gap created by the scratch. (B) Bar graph showing the percentage of wound closure of MDA-MB-231 cells after treatment with JE22 and JE22-NPs (5) compared to untreated cell control (DMSO) and cells treated with Naked-NPs (1), respectively. Error bars: ±SD from n = 3; p < 0.01, **; p < 0.001, *** (ANOVA).