Table 2.
List of HLA-A*02:01 class-I and HLA-DRB1*01:01 class-II peptides derived from the hPAP42mer sequence.
| HHDII/DR1 Mice | Sequence | Haplotype | Length | SYFPEITHI Score hPAP42mer WT |
SYFPEITHI Score hPAP42mer Mut |
|---|---|---|---|---|---|
| Class I epitopes | SAMTNLAAL | HLA-A*02:01 | 9 mer | 24 | 30 |
| ILLWQPIPV | 9 mer | 24 | 24 | ||
| ALFPPEGVSI | HLA-A*02:01/A*03 | 10 mer | 27/25 | 27/25 | |
| Class II epitopes | LAALFPPEGVSIWNP | HLA-DRB1*01:01 | 15 mer | 25 | 25 |
| MSAMTNLAALFPPEG | 15 mer | 33 | 33 | ||
| PEGVSIWNPILLWQP | 15 mer | 25 | 25 | ||
| VSIWNPILLWQPIPV | 15 mer | 25 | 25 | ||
| DRTLMSAMTNLAALF | 15 mer | 22 | 30 |