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. 2022 Apr 8;14(4):818. doi: 10.3390/pharmaceutics14040818

Table 4.

Hygroscopicity of powder materials at specific times.

MC a (%)
0 h 0.25 h 0.5 h 1 h 3 h 8 h 24 h 72 h 120 h 168 h 720 h
CELLULOSES
Avicel® PH 101 2.9 4.6 4.5 5.1 5.6 5.7 5.7 5.7 5.8 6.2 7.3
Methocel® E4M 3.6 3.6 3.7 3.7 3.7 3.8 4.0 4.8 4.9 5.4 7.7
Methocel® K100LV 4.7 4.5 4.6 4.7 5.0 5.1 5.1 5.2 7.1 7.7 8.2
SILICAS and SILICATES
Aerosil® 200 1.6 1.6 1.7 1.7 1.7 1.9 1.9 2.4 2.4 2.7 3.0
FujiSil® 4.0 4.1 4.3 4.8 4.8 4.9 5.0 5.0 5.6 6.0 7.8
Neusilin® NS2N 6.6 7.0 7.7 7.7 7.8 7.9 8.4 8.5 8.9 9.5 9.8
Neusilin® S2 7.2 7.4 7.7 7.7 7.9 8.5 8.6 8.6 9.2 9.2 11.2
Neusilin® UFL2 8.2 8.2 8.4 8.5 8.5 8.6 9.0 9.3 10.7 12.6 13.8
Neusilin® US2 4.6 8.1 8.5 8.7 8.9 8.9 9.2 9.4 9.6 10.6 14.9
Sipernat® 22S 5.3 5.5 5.6 5.6 5.7 5.9 6.0 6.5 5.6 7.2 7.5
Syloid® 244FP 3.6 4.2 4.2 4.3 4.7 4.8 4.9 5.0 5.0 5.5 8.6
Syloid® XDP 3050 3.4 4.1 4.4 4.4 4.4 4.5 4.8 5.2 5.8 6.0 6.2
CLAY MINERALS
Bentonite 7.2 7.2 7.3 7.4 7.7 7.8 7.9 8.0 8.2 8.6 9.5
Vermiculite 4.5 4.5 4.6 4.8 4.9 4.9 4.9 5.3 5.4 5.4 4.9

a Moisture content.