Table 4.
Source, extract/compound, activity and corresponding reference are reported.
| Source | Sponge Host | Extract/Compound | Activity | Reference |
|---|---|---|---|---|
| P. simplex | Plakortin and Plakortide Q | Antiplasmodial | [111] | |
| Hymeniacidon sp. | Monoamphilectine A | Antiplasmodial | [78] | |
| M. unguiculata | Ptilomycalin F and Fromiamycalin | Antiplasmodial | [112] | |
| F.reticulata | 8-oxo-tryptamine and (E)-6-bromo-20-demethyl-30-N-methylaplysinopsin and (Z)-6-bromo-20-demethyl-30-N-methylaplysinopsin | Antiplasmodial | [99] | |
| H. intestinalis | Bacterial colonies THB20 and THB34 | Ethyl acetate extract | Antiplasmodial | [113] |
| P. johnstonii | Pachymatismin | Antileishmanial | [114] | |
| H. exigua | Araguspongin C | Antileishmanial | [115] | |
| Hyrtios sp. | Hyrtiodoline A | Antitrypanosomial | [116] | |
| A. oroides | Ethanol extract | Antifungal | [79] | |
| H. communis | Untenospongin B | Antifungal | [119] | |
| S. carnosus and Leucosolenia sp. | Psedoalteromonas, Bacillus, Vibrio and Staphylococcus phyla | Isolated of bacteria | Antifungal | [93] |
| S. officinalis | Bacillus 2011SOCCUF3 | Methanol extract | Antifungal | [88] |
| N. exigua | Methanolic extract | Antifungal | [77] | |
| S. fortis | Peptide C | Antifungal | [81] | |
| P. angulospigulatus | Plakortide N and Plakortide F | Antifungal | [75] | |
| Plakortis sp. | Menzamenone M and Menzamenone N | Antifungal | [74] | |
| E. deficiens | Proteobacteria, Actinobacteria and Firmicutes phyla | Aqueous extract | Antifungal | [71] |
| Psammaplysilla sp. 1 | Ethyl acetate extract | Antifungal | [120] | |
| C. reniformis | Collagen extract | Wound-healing | [121] | |
| I. oros and S. foetidus | Collagen filaments | Wound-healing | [122] |