Table 6.
Country | Sex | Age (years) | Dose | Frequency/Days of Intervention | Sample Size | Design Study | Notes about Participants | Main Results | Ref. | ||
---|---|---|---|---|---|---|---|---|---|---|---|
M | F | Exp. | CT | ||||||||
Infusion/Decoction/Tea | |||||||||||
Indonesia | 0 | 18 | >60 | 2 g twice a day | 21 days | 9 | 9 | Q, CT | Subjects with metabolic syndrome | HS reduced body weight vs. control group (pretest/posttest) | [112] |
Capsule/Tablet | |||||||||||
China | 21 | 15 | 18–65 | 450 mg | 12 weeks | 19 | 17 | DBT, R | Obese subjects | HS reduced obesity and abdominal fat | [20] |
Spain | 0 | 55 | 36–69 | 250 mg HS mixture with Lippia citriodora (LC) |
8 weeks | 29 | 26 | R, DBT, PC | Healthy women 24–34 kg/m2 | The LC-HS groups showed a more significant decrease in body weight abdominal circumference, mainly in overweight individuals | [21] |
USA | NI | NI | 18–64 | 175 mg HS, 375 mg LC |
84 days | 42 | 42 | R, PC, DBT | Healthy subjects | LC-HS significantly decreased body weight | [130] |
HS: Hibiscus sabdariffa; M: male; F: female; Exp: experimental group; CT: control group; Q: quasi-experimental; vs: versus; DBT: double-blind trial; R: randomized trial; LC: Lippia citriodora; PC: placebo control; NI: no information.