Comparative analysis of gut microbial content in Sham Vs. TAC mice. (A) Box plot showing relative abundances of the total of 7 genera that were found to be differentially abundant using Wilcoxon’s test in the Sham and TAC comparison, indicating that most of the genera were found to be more abundant in Sham samples as compared to TAC samples (*, **, and *** correspond to p ≤ 0.05, p ≤ 0.01, and p ≤ 0.001, respectively). (n values are as follows: Sham = 38, TAC = 63). (B) Heat-tree showing significantly different genera in the Sham and TAC comparison using Wilcoxon’s test (p-value ≤ 0.05). (n values are as follows: Sham = 38, TAC = 63).