Figure 1.

Childhood obesity is linked to alterations in gene expression profiles in adipose tissue. (A) Venn diagram displaying the number of significant (False discovery rate FDR ≤ 5%) transcripts for each tissue (i.e., adipose tissue, adipocytes, and stromal vascular fraction (SVF) cells). The numbers in brackets after the labels correspond to the absolute number of significant transcripts for the respective tissues. (B) Scatter plots of pairwise comparisons of the effect sizes between tissues. Transcripts expressed in all tissues (M = 20,664) were considered. Common significant transcripts (FDR ≤ 5% for each tissue) are red coloured. The regression line was estimated on the basis of the respective effect sizes.